CNGB1

Across TCGA pan-cancer cohorts, CNGB1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated CNGB1 data layer compared with 9 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher CNGB1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNGB1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and STAD show a favorable association.

KIRC, KIRP, and CESC are the cancer types where CNGB1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.536	0.690	<.001	152	view →
KIRP	OS	Quartile	All	0.791	0.953	<.001	79	view →
CESC	DFS	Tertile	III,IV	0.305	0.816	.010	64	view →
PAAD	OS	Median	II,III,IV	0.481	0.665	<.001	49	view →
UCEC	DFS	Quartile	All	0.646	0.827	<.001	48	view →
COAD	DFS	Tertile	II,III,IV	0.512	0.777	<.001	36	view →
LUAD	DFS	Median	All	0.742	0.570	.004	31	view →
UVM	OS	Median	III,IV	0.240	0.836	.001	25	view →
ACC	DFS	Quartile	III,IV	0.064	0.569	.006	23	view →
BRCA	DFS	Quartile	III,IV	0.790	0.911	.002	22	view →
BLCA	DFS	Median	III,IV	0.274	0.448	.016	20	view →
LIHC	DFS	Median	II,III,IV	0.329	0.570	.010	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

CNGB1–KIRC (DFS)

Open the KIRC breakdown →