CNGB1

Across TCGA cell cohorts, CNGB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,782 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CNGB1-associated GO terms across cancer lineages are Establishment of endothelial barrier, T cell mediated cytotoxicity, and Negative regulation of RNA catabolic process. Each is linked with CNGB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CNGB1-to-partner and partner-to-CNGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of endothelial barrier grouped by CNGB1-low versus CNGB1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNGB1→partner) and Y-score (partner→CNGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Establishment of endothelial barrier →	+0.107	+0.634	<.001	<.001	3	7
LUNG_NSCLC_LUAD	T cell mediated cytotoxicity →	+0.184	+0.491	.001	.001	3	7
BREAST	Negative regulation of RNA catabolic process →	+0.066	+0.708	<.001	.004	3	6
PANCREAS	Positive regulation of complement activation →	+0.817	+0.343	.007	<.001	3	6
PANCREAS	Cellular response to indole-3-methanol →	+0.129	+0.396	.003	.006	2	7
OESOPHAGUS	Delamination →	-0.206	-0.452	<.001	.004	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,782 associations by consensus.

Establishment of endothelial barrier by CNGB1 expression — OVARY

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