CNFN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CNFN protein abundance is significantly associated with the protein abundance of many other proteins, with 5,084 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNFN-associated proteins across cancer lineages are ANK2_S3765, ARL6IP4, and RPL21. Each is linked with CNFN in more than 1 cancer types. Because this analysis shows association rather than direction, both CNFN-to-partner and partner-to-CNFN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CNFN versus ANK2_S3765 in HNSC, with a Pearson correlation of -0.51.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CNFN→partner) and Y-score (partner→CNFN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCANK2_S3765 →-1.160-0.788<.001<.00131
HNSCARL6IP4 →-0.269-0.526.004.00231
HNSCRPL21 →+0.245+0.743<.001<.00131
HNSCRPL3_S350 →+1.571+0.729<.001<.00131
HNSCRPS2 →+0.216+0.647.001<.00131
HNSCRPS6KA1_S363 →+0.281+0.591<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,084 associations by consensus.

CNFN vs ANK2_S3765 — HNSC

Per-sample scatter of CNFN vs ANK2_S3765 in HNSC (Pearson r = -0.51).

Explore this scatter interactively →

Exploration