CNFN

Across TCGA cell cohorts, CNFN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,141 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CNFN-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Regulation of syncytium formation by plasma membrane fusion. Each is linked with CNFN in more than 9 cancer types. Because this analysis shows association rather than direction, both CNFN-to-partner and partner-to-CNFN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by CNFN-low versus CNFN-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNFN→partner) and Y-score (partner→CNFN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of myoblast fusion →	+0.112	+1.307	.002	.006	3	10
BLOOD_Leukemia	Negative regulation of syncytium formation by plasma membrane fusion →	+0.092	+1.001	<.001	<.001	3	10
STOMACH	Regulation of syncytium formation by plasma membrane fusion →	+0.102	+1.412	.002	.003	3	9
LUNG_NSCLC_LUSC	Regulation of proteasomal protein catabolic process →	+0.074	+1.658	.003	.001	3	9
STOMACH	Regulation of myoblast fusion →	+0.105	+1.420	.002	.002	3	8
STOMACH	Aerobic electron transport chain →	+0.111	+1.914	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,141 associations by consensus.

Negative regulation of myoblast fusion by CNFN expression — STOMACH

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