CNDP2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNDP2 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CNDP2-associated genes across cancer lineages are NPY, NAA11, and C10orf53. Each is linked with CNDP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CNDP2-to-partner and partner-to-CNDP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NPY grouped by CNDP2-low versus CNDP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNDP2→partner) and Y-score (partner→CNDP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINENPY →+0.051+2.874.007.00831
LARGE_INTESTINENAA11 →+0.345+3.443.002.00931
LARGE_INTESTINEC10orf53 →+0.010+3.217.002.00631
LARGE_INTESTINETAFA1 →+0.234+3.103.002.00431
LARGE_INTESTINEC14orf180 →+0.151+3.155<.001.00831
LARGE_INTESTINESMIM33 →+0.793+3.426<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

NPY by CNDP2 expression — LARGE_INTESTINE

Box plot of NPY in CNDP2-low vs CNDP2-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration