CNBP

Across TCGA pan-cancer cohorts, CNBP mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated CNBP data layer compared with 25 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CNBP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CNBP expression acts as an unfavorable survival marker, although some lineages such as LSCC and LUAD show a favorable association.

COAD, CCRCC, and LSCC are the cancer types where CNBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.909	1.000	.010	48	view →
CCRCC	DFS	Quartile	All	0.558	1.000	.001	31	view →
LSCC	DFS	Tertile	All	0.841	0.510	.004	19	view →
LUAD	OS	Median	III,IV	0.823	0.335	.005	17	view →
OV	DFS	Median	All	1.000	0.845	.022	4	view →
UCEC	OS	Median	All	0.902	0.985	.017	4	view →
GBM	OS	Tertile	All	0.618	0.273	.046	3	view →
HNSC	DFS	Median	II,III,IV	0.745	0.571	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

CNBP–COAD (DFS)

Open the COAD breakdown →