CNBP

Across TCGA patient cohorts, CNBP mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNBP-associated genes across cancer lineages are eIF4E, p62 Lck ligand, and ATM. Each is linked with CNBP in more than 1 cancer types. Because this analysis shows association rather than direction, both CNBP-to-partner and partner-to-CNBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eIF4E grouped by CNBP-low versus CNBP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNBP→partner) and Y-score (partner→CNBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.229	+2.820	.048	.035	3	1
UCEC	p62 Lck ligand →	+0.527	+3.169	.003	.020	3	1
UCEC	ATM →	-0.650	-3.169	.008	.020	3	1
UCEC	FOXO3a_pS318_S321 →	-0.160	-3.169	.019	.020	1	1
UCEC	Annexin-1 →	+0.971	+3.169	<.001	.020	1	1
UCEC	4E-BP1 →	+0.339	+3.169	.022	.020	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

eIF4E by CNBP expression — UCEC

Explore this box plot interactively →