CNBP

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CNBP mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CNBP-associated genes across cancer lineages are OR10W1, TEX55, and OR11H6. Each is linked with CNBP in more than 1 cancer types. Because this analysis shows association rather than direction, both CNBP-to-partner and partner-to-CNBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by CNBP-low versus CNBP-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNBP→partner) and Y-score (partner→CNBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR10W1 →+0.022+4.977<.001.00731
CNSTEX55 →+0.049+5.321<.001.00531
CNSOR11H6 →+0.021+5.321<.001.00531
CNSFGF3 →+0.040+4.981.001.00831
CNSDPRX →+0.064+5.321<.001.00531
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR10W1 by CNBP expression — LARGE_INTESTINE

Box plot of OR10W1 in CNBP-low vs CNBP-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration