CNBD2

Across TCGA patient cohorts, CNBD2 mutation is significantly associated with the RNA expression of many other genes, with 800 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CNBD2-associated genes across cancer lineages are LINC00709, RN7SL840P, and ADAM20P3. Each is linked with CNBD2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CNBD2-to-partner and partner-to-CNBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00709 grouped by CNBD2-low versus CNBD2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CNBD2→partner) and Y-score (partner→CNBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	LINC00709 →	+0.088	+5.142	.002	.002	3	3
BLCA	RN7SL840P →	+0.345	+4.238	<.001	.008	3	2
LUAD	ADAM20P3 →	+0.256	+2.908	<.001	.006	3	2
BLCA	RNU6-1318P →	+0.253	+4.588	.003	.008	3	2
HNSC	TRAJ52 →	+0.488	+4.826	<.001	.001	3	2
UCEC	TPRN →	+0.447	+2.708	.006	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 800 associations by consensus.

LINC00709 by CNBD2 expression — COAD

Explore this box plot interactively →