CNBD2

Across TCGA cell cohorts, CNBD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,733 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CNBD2-associated GO terms across cancer lineages are Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway, Respiratory chain complex II assembly, and Mitochondrial respiratory chain complex II assembly. Each is linked with CNBD2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CNBD2-to-partner and partner-to-CNBD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway grouped by CNBD2-low versus CNBD2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CNBD2→partner) and Y-score (partner→CNBD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway →	+0.109	+0.779	.002	.009	3	8
CNS	Respiratory chain complex II assembly →	+0.074	+0.725	<.001	<.001	3	8
CNS	Mitochondrial respiratory chain complex II assembly →	+0.074	+0.725	<.001	<.001	3	8
BONE	Mitochondrial respiratory chain complex assembly →	+0.069	+0.490	.008	.009	2	9
LUNG_NSCLC_LUSC	Regulation of leukocyte migration →	-0.090	-1.231	.001	.004	3	7
LUNG_NSCLC_LUSC	Positive regulation of chemotaxis →	-0.150	-2.082	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,733 associations by consensus.

Co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway by CNBD2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →