CMYA5

Across TCGA cell cohorts, CMYA5 mutation is significantly associated with the RNA expression of many other genes, with 981 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CMYA5-associated genes across cancer lineages are ZIC2, KDSR, and DYNC1LI1. Each is linked with CMYA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both CMYA5-to-partner and partner-to-CMYA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZIC2 grouped by CMYA5-low versus CMYA5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMYA5→partner) and Y-score (partner→CMYA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZIC2 →	+1.099	+2.145	.004	.006	3	3
LARGE_INTESTINE	KDSR →	+0.791	+2.043	<.001	<.001	3	3
LARGE_INTESTINE	DYNC1LI1 →	+0.389	+3.584	<.001	<.001	3	3
LARGE_INTESTINE	CDC123 →	+0.437	+1.706	.002	<.001	3	3
LARGE_INTESTINE	DCK →	+0.561	+1.706	<.001	<.001	3	3
LARGE_INTESTINE	RFC4 →	+0.490	+2.115	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 981 associations by consensus.

ZIC2 by CMYA5 expression — BLOOD_Leukemia

Explore this box plot interactively →