CMTR1

Across TCGA pan-cancer cohorts, CMTR1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CMTR1 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CMTR1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CMTR1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, LSCC, and PDAC are the cancer types where CMTR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	III,IV	0.890	0.329	.012	16	view →
LSCC	DFS	Tertile	All	0.848	0.611	.011	16	view →
PDAC	DFS	Median	IV	0.785	0.214	.006	9	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →
UCEC	OS	Tertile	All	0.893	1.000	.021	6	view →
HNSC	DFS	Median	IV	1.000	0.924	.037	1	view →
CCRCC	OS	Tertile	III,IV	0.906	0.658	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CMTR1–LUAD (DFS)

Open the LUAD breakdown →