CMTM5

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CMTM5 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated CMTM5 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher CMTM5 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CMTM5 expression acts as an unfavorable survival marker.

GBM are the cancer types where CMTM5 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMOSMedianAll0.2280.550.0065view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

CMTM5–GBM (OS)

Kaplan–Meier survival curve for CMTM5 mass-spec protein-high vs -low samples in GBM.

Open the GBM breakdown →

Exploration