CMTM5

Across TCGA cell cohorts, CMTM5 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CMTM5-associated genes across cancer lineages are CXorf51A, MEIKIN, and MSGN1. Each is linked with CMTM5 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMTM5-to-partner and partner-to-CMTM5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CXorf51A grouped by CMTM5-low versus CMTM5-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTM5→partner) and Y-score (partner→CMTM5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CXorf51A →	+0.076	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	MEIKIN →	+0.085	+4.887	.002	.009	3	1
LARGE_INTESTINE	MSGN1 →	+0.100	+3.930	<.001	.003	3	1
LARGE_INTESTINE	CD300H →	+0.044	+5.000	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CXorf51A by CMTM5 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →