Across TCGA patient cohorts, CMTM4 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,941 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CMTM4-associated proteins across cancer lineages are BTK, ADGRG1, and CD48. Each is linked with CMTM4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CMTM4-to-partner and partner-to-CMTM4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CMTM4→partner) and Y-score (partner→CMTM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	BTK →	-0.492	-0.529	<.001	<.001	3	6
GBM	ADGRG1 →	+0.603	+0.973	<.001	<.001	3	6
BRCA	CD48 →	-0.696	-0.513	<.001	.006	3	6
GBM	TRAF3IP3 →	-0.654	-0.795	<.001	.001	3	6
LSCC	RASAL3 →	-0.446	-0.602	<.001	<.001	3	6
UCEC	CIAPIN1 →	+0.260	+0.768	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,941 associations by consensus.

Exploration

CMTM4 survival (RNA) · tumor vs normal (RNA) · all CMTM4 data types