Across TCGA patient cohorts, CMSS1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,266 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CMSS1-associated genes across cancer lineages are CSE1L, WDR74, and DSCC1. Each is linked with CMSS1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CMSS1-to-partner and partner-to-CMSS1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMSS1→partner) and Y-score (partner→CMSS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CSE1L →	+0.588	+0.441	.002	<.001	3	8
UCEC	WDR74 →	+0.596	+0.428	<.001	.001	3	8
BRCA	DSCC1 →	+0.874	+0.598	<.001	<.001	3	8
LSCC	HSPD1 →	+0.865	+0.740	<.001	<.001	3	8
UCEC	CDC25C →	+1.312	+0.513	<.001	<.001	3	8
HNSC	WDR43 →	+0.881	+0.493	.003	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,266 associations by consensus.

Exploration

CMSS1 survival (RNA) · tumor vs normal (RNA) · all CMSS1 data types