CMC4

Across TCGA patient cohorts, CMC4 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMC4-associated genes across cancer lineages are Endothelial cells and mv Endothelial cells. Each is linked with CMC4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMC4-to-partner and partner-to-CMC4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endothelial cells grouped by CMC4-low versus CMC4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMC4→partner) and Y-score (partner→CMC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Endothelial cells →	-0.046	-3.127	.027	.020	3	1
UCEC	mv Endothelial cells →	-0.028	-3.159	.029	.020	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Endothelial cells by CMC4 expression — UCEC

Explore this box plot interactively →