CMAHP

Across TCGA patient cohorts, CMAHP mutation is significantly associated with the RNA expression of many other genes, with 3,401 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CMAHP-associated genes across cancer lineages are RN7SL248P, DYNLT3P2, and YTHDF3-AS1. Each is linked with CMAHP in more than 1 cancer types. Because this analysis shows association rather than direction, both CMAHP-to-partner and partner-to-CMAHP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CMAHP-low versus CMAHP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMAHP→partner) and Y-score (partner→CMAHP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.049	+2.915	<.001	.007	3	2
UCEC	DYNLT3P2 →	+0.301	+1.918	<.001	.002	3	2
UCEC	YTHDF3-AS1 →	+0.615	+1.979	<.001	.002	3	1
UCEC	RPS10-NUDT3 →	+0.205	+2.321	.002	.001	3	1
UCEC	KRT8P49 →	+0.272	+3.669	<.001	.001	3	1
UCEC	NUDT3 →	+0.328	+3.818	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,401 associations by consensus.

RN7SL248P by CMAHP expression — UCEC

Explore this box plot interactively →