CMA1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CMA1 protein abundance is significantly associated with the RNA expression of many other genes, with 13,039 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CMA1-associated genes across cancer lineages are CTSG, MS4A2, and CPA3. Each is linked with CMA1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CMA1-to-partner and partner-to-CMA1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CMA1 versus CTSG in BRCA, with a Pearson correlation of 0.72.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMA1→partner) and Y-score (partner→CMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACTSG →+1.550+1.018<.001<.00139
BRCAMS4A2 →+1.439+1.080<.001<.00139
BRCACPA3 →+2.130+1.000<.001<.00139
BRCATPSAB1 →+1.999+0.933<.001<.00139
BRCAPODN →+1.473+0.812<.001<.00139
OVADH1B →+2.332+1.051<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,039 associations by consensus.

CMA1 vs CTSG — BRCA

Per-sample scatter of CMA1 vs CTSG in BRCA (Pearson r = 0.72).

Explore this scatter interactively →

Exploration