CMA1

Across TCGA cell cohorts, CMA1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CMA1-associated genes across cancer lineages are NLRP8 and OR1P1. Each is linked with CMA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CMA1-to-partner and partner-to-CMA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NLRP8 grouped by CMA1-low versus CMA1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CMA1→partner) and Y-score (partner→CMA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	NLRP8 →	+0.054	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR1P1 →	+0.065	+4.887	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

NLRP8 by CMA1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →