CLYBL

Across TCGA patient cohorts, CLYBL protein abundance is significantly associated with the RNA expression of many other genes, with 13,345 significant associations in total. COAD shows the largest number of these associations.

The most reproducible CLYBL-associated genes across cancer lineages are FN1, EPHX2, and PPP1R18. Each is linked with CLYBL in more than 4 cancer types. Because this analysis shows association rather than direction, both CLYBL-to-partner and partner-to-CLYBL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLYBL versus FN1 in OV, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLYBL→partner) and Y-score (partner→CLYBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FN1 →	-1.613	-0.479	<.001	<.001	3	5
BRCA	EPHX2 →	+0.953	+0.561	<.001	<.001	3	5
OV	PPP1R18 →	-0.937	-0.499	<.001	<.001	3	5
UCEC	CRYL1 →	+0.733	+0.522	.002	<.001	3	5
OV	PLAU →	-1.168	-0.477	<.001	<.001	3	5
OV	PLOD1 →	-0.891	-0.571	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,345 associations by consensus.

CLYBL vs FN1 — OV

Explore this scatter interactively →