CLYBL

Across TCGA patient cohorts, CLYBL mutation is significantly associated with the RNA expression of many other genes, with 1,388 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLYBL-associated genes across cancer lineages are RN7SL607P, MIR3912, and SNORD116-16. Each is linked with CLYBL in more than 2 cancer types. Because this analysis shows association rather than direction, both CLYBL-to-partner and partner-to-CLYBL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL607P grouped by CLYBL-low versus CLYBL-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLYBL→partner) and Y-score (partner→CLYBL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL607P →	+0.391	+4.575	<.001	.009	3	3
UCEC	MIR3912 →	+0.276	+2.152	<.001	.009	3	3
SKCM	SNORD116-16 →	+0.537	+3.693	<.001	<.001	3	3
CESC	RNA5SP432 →	+0.349	+5.539	<.001	.004	3	2
BRCA	RNU2-34P →	+0.360	+5.064	.009	.004	3	2
BRCA	NDE1P2 →	+0.051	+5.112	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,388 associations by consensus.

RN7SL607P by CLYBL expression — BRCA

Explore this box plot interactively →