CLYBL-AS1

Across TCGA pan-cancer cohorts, CLYBL-AS1 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated CLYBL-AS1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher CLYBL-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated CLYBL-AS1 expression acts as an unfavorable survival marker, although some lineages such as BLCA and LGG show a favorable association.

DLBC, BRCA, and PAAD are the cancer types where CLYBL-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Quartile	III,IV	0.129	0.797	<.001	52	view →
BRCA	DFS	Tertile	II,III,IV	0.770	0.895	.001	24	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
BLCA	OS	Tertile	II,III,IV	0.762	0.590	.029	15	view →
OV	OS	Quartile	IV	0.348	0.688	.002	14	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
PCPG	OS	Tertile	All	0.786	0.963	<.001	9	view →
COAD	OS	Tertile	IV	0.212	0.677	.044	9	view →
LGG	OS	Quartile	All	0.952	0.870	.004	9	view →
READ	DFS	Tertile	IV	0.095	0.697	.014	9	view →
LUAD	DFS	Tertile	All	0.814	0.322	.039	6	view →
LIHC	OS	Tertile	All	0.875	0.672	.045	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

CLYBL-AS1–DLBC (OS)

Open the DLBC breakdown →