CLYBL-AS1

Across TCGA pan-cancer cohorts, CLYBL-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of CLYBL-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CLYBL-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CLYBL-AS1 is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC, BRCA, and LUAD are the cancer types where CLYBL-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLYBL-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	All	All	−0.103	<.001	5	view →
BRCA	Female	All	+0.079	.041	2	view →
LUAD	Female	II,III,IV	−0.161	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

CLYBL-AS1–LUSC

Open the LUSC breakdown →