CLVS1

Across TCGA patient cohorts, CLVS1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,542 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLVS1-associated proteins across cancer lineages are SND1_S645, STXBP1, and MAP2_S862. Each is linked with CLVS1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLVS1-to-partner and partner-to-CLVS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLVS1 versus SND1_S645 in CCRCC, with a Pearson correlation of -0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLVS1→partner) and Y-score (partner→CLVS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SND1_S645 →	-0.778	-0.091	<.001	.001	3	4
GBM	STXBP1 →	+0.709	+0.671	<.001	.005	3	4
LUAD	MAP2_S862 →	+1.307	+0.232	<.001	<.001	3	4
LUAD	ARHGEF1_S631 →	-0.853	-0.126	<.001	.002	3	4
LSCC	RETREG2_S385 →	+0.836	+0.197	<.001	<.001	3	3
LUAD	RICTOR_S1388 →	+1.036	+0.270	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,542 associations by consensus.

CLVS1 vs SND1_S645 — CCRCC

Explore this scatter interactively →