Q-omics provides the consensus-scored CLUHP8 profile across patient tissues and cancer cell-line models. CLUHP8 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, CLUHP8 is differentially expressed in 1, with the highest sampling consensus in KIRC. Additionally, CLUHP8 RNA expression shows 6,779 significant gene co-expression associations, with the highest sampling consensus in LUSC. Together, these results highlight KIRC, and LUSC as cancer lineages where CLUHP8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CLUHP8 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CLUHP8 survival associations across molecular data types. CLUHP8 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CLUHP8 RNA expression–survival associations across cancer types. High CLUHP8 expression shows unfavorable associations in KIRC, THCA, BLCA, KICH, BRCA and DLBC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KIRC as the clearest survival context for CLUHP8 RNA expression.
This table summarizes CLUHP8 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for CLUHP8. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CLUHP8 shows lower tumor expression in KIRC. The KIRC box plot shows higher CLUHP8 RNA expression in normal versus tumor tissue (log2 FC = −0.010, t-test p = .024).
This table shows molecular features associated with CLUHP8 in patient tissues and cancer cell lines. In patient samples, CLUHP8 shows the broadest associations at the RNA and protein expression levels, with LUSC recurring as the lineage with the largest associated feature set.
