CLUAP1

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CLUAP1 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CLUAP1 data layer compared with 20 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher CLUAP1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLUAP1 expression acts as an unfavorable survival marker.

CESC, LIHC, and UCEC are the cancer types where CLUAP1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCDFSMedianIII,IV0.2400.726.0156view →
LIHCOSMedianAll0.1770.783.0036view →
UCECOSMedianIV0.2310.592.0366view →
KIRPOSMedianAll0.2480.705.0492view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CLUAP1–CESC (DFS)

Kaplan–Meier survival curve for CLUAP1 mutant vs wild-type samples in CESC.

Open the CESC breakdown →

Exploration