CLUAP1

Across TCGA pan-cancer cohorts, CLUAP1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CLUAP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CLUAP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CLUAP1 is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

KIRP, KICH, and BLCA are the cancer types where CLUAP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLUAP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	II,III,IV	+0.803	<.001	10	view →
KICH	Female	II,III,IV	−1.678	<.001	9	view →
BLCA	Male	III,IV	−1.605	<.001	8	view →
LIHC	All	II,III,IV	+0.616	<.001	8	view →
THCA	All	II,III,IV	−0.303	.004	8	view →
UCEC	All	All	−0.955	<.001	6	view →
CHOL	All	All	+2.134	<.001	5	view →
HNSC	Male	All	+0.399	.020	5	view →
LUSC	All	II,III,IV	−0.492	.006	4	view →
COAD	All	All	+0.353	.005	4	view →
PRAD	All	All	−0.257	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CLUAP1–KIRP

Open the KIRP breakdown →