CLUAP1

Across TCGA pan-cancer cohorts, CLUAP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CLUAP1 data layer compared with 20 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CLUAP1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLUAP1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

HNSC, LSCC, and LUAD are the cancer types where CLUAP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	DFS	Tertile	III,IV	0.688	0.968	.006	41	view →
LSCC	DFS	Quartile	II,III,IV	0.846	1.000	.007	7	view →
LUAD	OS	Quartile	II,III,IV	1.000	0.351	.010	7	view →
UCEC	OS	Median	All	0.859	0.966	.040	4	view →
PDAC	DFS	Tertile	All	0.650	0.349	.044	4	view →
GBM	OS	Median	All	0.637	0.887	.008	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CLUAP1–HNSC (DFS)

Open the HNSC breakdown →