CLUAP1

Across TCGA patient cohorts, CLUAP1 mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLUAP1-associated genes across cancer lineages are Akt_pS473, p70-S6K, and Rad50. Each is linked with CLUAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLUAP1-to-partner and partner-to-CLUAP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Akt_pS473 grouped by CLUAP1-low versus CLUAP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLUAP1→partner) and Y-score (partner→CLUAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Akt_pS473 →	+0.660	+1.678	.016	.023	3	2
UCEC	p70-S6K →	+0.168	+2.479	.022	.010	3	2
UCEC	Rad50 →	-0.212	-1.678	.022	.023	3	2
UCEC	ASNS →	+0.413	+2.115	.002	.017	3	2
UCEC	Caspase-7-cleavedD198 →	+0.713	+2.019	.001	.017	3	2
UCEC	FASN →	+0.473	+3.169	.001	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

Akt_pS473 by CLUAP1 expression — UCEC

Explore this box plot interactively →