CLU

Across TCGA patient cohorts, CLU protein abundance is significantly associated with the RNA expression of many other genes, with 13,286 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLU-associated genes across cancer lineages are PRELP, CCN2, and IGFBP7. Each is linked with CLU in more than 5 cancer types. Because this analysis shows association rather than direction, both CLU-to-partner and partner-to-CLU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLU versus PRELP in COAD, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLU→partner) and Y-score (partner→CLU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PRELP →	+1.308	+0.616	<.001	<.001	3	6
COAD	CCN2 →	+1.295	+0.789	<.001	<.001	3	6
GBM	IGFBP7 →	+0.829	+0.562	<.001	.001	3	5
CCRCC	LINC00702 →	+0.579	+0.790	<.001	<.001	3	5
GBM	SLC16A10 →	+1.206	+0.726	<.001	<.001	3	4
COAD	SNAI1 →	+0.884	+0.598	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,286 associations by consensus.

CLU vs PRELP — COAD

Explore this scatter interactively →