CLTRN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLTRN protein abundance is significantly associated with the RNA expression of many other genes, with 1,132 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CLTRN-associated genes across cancer lineages are UPB1, SLC35E4, and LGALS2. Each is linked with CLTRN in more than 1 cancer types. Because this analysis shows association rather than direction, both CLTRN-to-partner and partner-to-CLTRN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLTRN versus UPB1 in CCRCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTRN→partner) and Y-score (partner→CLTRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCUPB1 →+1.124+0.439.001.00131
CCRCCSLC35E4 →-0.273-0.469.002<.00131
CCRCCLGALS2 →+1.085+0.402.003.00131
CCRCCRSPH14 →+0.723+0.454<.001<.00131
CCRCCRAB36 →+0.594+0.477.005<.00131
CCRCCHMOX1 →+0.752+0.396.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,132 associations by consensus.

CLTRN vs UPB1 — CCRCC

Per-sample scatter of CLTRN vs UPB1 in CCRCC (Pearson r = 0.44).

Explore this scatter interactively →

Exploration