CLTRN

Across TCGA cell cohorts, CLTRN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,527 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLTRN-associated GO terms across cancer lineages are COPII vesicle coating, Regulation of syncytium formation by plasma membrane fusion, and Vesicle targeting. Each is linked with CLTRN in more than 8 cancer types. Because this analysis shows association rather than direction, both CLTRN-to-partner and partner-to-CLTRN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COPII vesicle coating grouped by CLTRN-low versus CLTRN-high in CNS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLTRN→partner) and Y-score (partner→CLTRN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	COPII vesicle coating →	+0.092	+0.499	<.001	<.001	3	9
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.079	+0.437	.002	.002	3	8
LUNG_SCLC	Vesicle targeting →	+0.075	+0.502	<.001	.001	3	8
LIVER	Vesicle tethering →	+0.082	+2.163	.001	.002	3	7
LUNG_SCLC	Vesicle targeting, rough ER to cis-Golgi →	+0.087	+0.465	.002	.003	3	7
LIVER	Vesicle budding from membrane →	+0.072	+1.392	.001	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,527 associations by consensus.

COPII vesicle coating by CLTRN expression — CNS

Explore this box plot interactively →