CLSTN2-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CLSTN2-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated CLSTN2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher CLSTN2-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CLSTN2-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and UCS show a favorable association.

ACC, UCS, and CHOL are the cancer types where CLSTN2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCDFSTertileAll0.7230.288<.00185view →
UCSDFSTertileII,III,IV0.5990.128<.00162view →
CHOLOSTertileIII,IV0.1620.915.00436view →
UCECDFSMedianIV0.7360.351.00424view →
MESODFSTertileAll0.7150.334.02524view →
LUSCDFSMedianAll0.7930.728.01123view →
KICHOSQuartileII,III,IV0.7320.941.00922view →
UVMOSMedianAll0.8780.463.01218view →
LUADOSTertileIV0.2620.618.04518view →
TGCTDFSQuartileAll0.4040.783.00312view →
PRADOSMedianAll0.9731.000.00412view →
PAADDFSMedianIII,IV0.1180.734.01412view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

CLSTN2-AS1–ACC (DFS)

Kaplan–Meier survival curve for CLSTN2-AS1 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration