CLSTN2-AS1

Across TCGA pan-cancer cohorts, CLSTN2-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CLSTN2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CLSTN2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CLSTN2-AS1 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and PAAD are the cancer types where CLSTN2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLSTN2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−0.209	<.001	8	view →
KICH	All	All	−0.225	<.001	7	view →
PAAD	Male	All	−0.075	.021	4	view →
LUSC	All	All	+0.051	.002	2	view →
BLCA	All	All	+0.026	.039	2	view →
ESCA	All	II,III,IV	+0.025	.037	2	view →
THCA	Male	III,IV	−0.024	.018	2	view →
CHOL	All	All	+0.074	.048	1	view →
LUAD	All	All	+0.051	.046	1	view →
STAD	Male	All	+0.014	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CLSTN2-AS1–KIRP

Open the KIRP breakdown →