CLSPN

Across TCGA patient cohorts, CLSPN protein abundance is significantly associated with the RNA expression of many other genes, with 3,019 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLSPN-associated genes across cancer lineages are SMU1P1, PTH1R, and LINC01645. Each is linked with CLSPN in more than 2 cancer types. Because this analysis shows association rather than direction, both CLSPN-to-partner and partner-to-CLSPN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLSPN versus SMU1P1 in OV, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLSPN→partner) and Y-score (partner→CLSPN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMU1P1 →	+1.555	+1.230	<.001	<.001	3	3
UCEC	PTH1R →	-0.900	-0.803	.001	.003	3	2
UCEC	LINC01645 →	-1.352	-1.140	<.001	.002	3	2
LSCC	PRSS12 →	-1.099	-0.642	.004	.004	3	2
LSCC	RHOT1P2 →	-1.756	-0.798	<.001	<.001	3	2
LSCC	RAB7B →	-1.263	-0.835	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,019 associations by consensus.

CLSPN vs SMU1P1 — OV

Explore this scatter interactively →