CLRN2

Across TCGA cell cohorts, CLRN2 RNA expression is significantly associated with the mutation status of many other genes, with 70 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible CLRN2-associated genes across cancer lineages are ITGA8, GEMIN4, and SPTA1. Each is linked with CLRN2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CLRN2-to-partner and partner-to-CLRN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGA8 grouped by CLRN2-low versus CLRN2-high in LUNG_NSCLC_LUAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLRN2→partner) and Y-score (partner→CLRN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	ITGA8 →	+2.434	+0.021	.005	.002	3	3
BLOOD_Lymphoma	GEMIN4 →	+4.523	+0.036	.004	<.001	3	2
BREAST	SPTA1 →	+4.196	+0.024	.006	<.001	3	2
SOFT_TISSUE	AP1B1 →	+4.369	+0.019	.008	<.001	3	1
SOFT_TISSUE	CRTAM →	+5.369	+0.036	.004	<.001	3	1
SOFT_TISSUE	HADH →	+5.369	+0.015	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 70 associations by consensus.

ITGA8 by CLRN2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →