CLRN1

Across TCGA cell cohorts, CLRN1 RNA expression is significantly associated with the mutation status of many other genes, with 89 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CLRN1-associated genes across cancer lineages are PCDHA13, ADAM21, and ZNF197. Each is linked with CLRN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLRN1-to-partner and partner-to-CLRN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCDHA13 grouped by CLRN1-low versus CLRN1-high in URINARY_TRACT.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLRN1→partner) and Y-score (partner→CLRN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	PCDHA13 →	+5.087	+0.033	.004	<.001	3	2
LUNG_NSCLC_LUAD	ADAM21 →	+6.266	+0.033	<.001	<.001	3	2
LUNG_NSCLC_LUAD	ZNF197 →	+4.681	+0.020	.003	<.001	3	2
CNS	SLIT3 →	+4.169	+0.098	.008	<.001	3	2
OESOPHAGUS	SLIT2 →	+2.847	+0.015	.004	.009	3	1
PANCREAS	AHDC1 →	+3.321	+0.018	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 89 associations by consensus.

PCDHA13 by CLRN1 expression — URINARY_TRACT

Explore this box plot interactively →