CLPTM1

Across TCGA patient cohorts, CLPTM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,163 significant associations in total. THCA shows the largest number of these associations.

The most reproducible CLPTM1-associated GO terms across cancer lineages are Free ubiquitin chain polymerization, Establishment or maintenance of cytoskeleton polarity, and Maintenance of protein location in mitochondrion. Each is linked with CLPTM1 in more than 22 cancer types. Because this analysis shows association rather than direction, both CLPTM1-to-partner and partner-to-CLPTM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Free ubiquitin chain polymerization grouped by CLPTM1-low versus CLPTM1-high in TGCT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLPTM1→partner) and Y-score (partner→CLPTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
TGCT	Free ubiquitin chain polymerization →	+0.074	+0.617	<.001	<.001	3	23
SCLC	Establishment or maintenance of cytoskeleton polarity →	+0.141	+0.604	.004	.002	1	23
TGCT	Maintenance of protein location in mitochondrion →	+0.049	+0.444	<.001	<.001	3	19
GBM	Humoral immune response →	-0.048	-0.392	<.001	<.001	3	19
THYM	Positive regulation of isotype switching to IgA isotypes →	+0.059	+0.423	<.001	<.001	3	19
ACC	Antimicrobial humoral response →	-0.068	-1.010	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,163 associations by consensus.

Free ubiquitin chain polymerization by CLPTM1 expression — TGCT

Explore this box plot interactively →