CLPTM1

Across TCGA patient cohorts, CLPTM1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,655 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLPTM1-associated genes across cancer lineages are TOMM40, FYCO1, and TNXB. Each is linked with CLPTM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CLPTM1-to-partner and partner-to-CLPTM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLPTM1 versus TOMM40 in LUAD, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLPTM1→partner) and Y-score (partner→CLPTM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOMM40 →	+0.637	+0.274	<.001	<.001	3	5
UCEC	FYCO1 →	-0.522	-0.467	.004	<.001	3	4
CCRCC	TNXB →	-1.079	-0.381	<.001	<.001	3	4
CCRCC	KLHDC1 →	-0.749	-0.403	<.001	<.001	3	4
UCEC	HTRA2 →	-0.909	-0.361	<.001	.002	3	4
UCEC	DYNC2H1 →	-0.735	-0.464	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,655 associations by consensus.

CLPTM1 vs TOMM40 — LUAD

Explore this scatter interactively →