Across TCGA patient cohorts, CLPSL2 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLPSL2-associated genes across cancer lineages are SEPTIN14P19, OR1D5, and RN7SKP224. Each is linked with CLPSL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLPSL2-to-partner and partner-to-CLPSL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLPSL2→partner) and Y-score (partner→CLPSL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SEPTIN14P19 →	+0.115	+7.245	<.001	<.001	3	1
UCEC	OR1D5 →	+0.136	+5.484	<.001	.005	3	1
UCEC	RN7SKP224 →	+0.281	+5.133	.002	.008	3	1
UCEC	SC4MOP →	+0.153	+6.453	<.001	.001	3	1
UCEC	CHEK2P5 →	+0.361	+5.358	<.001	.006	3	1
UCEC	RNU6-1213P →	+0.944	+6.877	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

Exploration

CLPSL2 survival (RNA) · tumor vs normal (RNA) · all CLPSL2 data types