CLN6

Across TCGA patient cohorts, CLN6 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,459 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLN6-associated proteins across cancer lineages are PRIM2, PRC1, and MCM3. Each is linked with CLN6 in more than 7 cancer types. Because this analysis shows association rather than direction, both CLN6-to-partner and partner-to-CLN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLN6 versus PRIM2 in GBM, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN6→partner) and Y-score (partner→CLN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRIM2 →	+0.483	+0.312	<.001	.002	3	8
LSCC	PRC1 →	+0.653	+0.505	<.001	<.001	3	7
LSCC	MCM3 →	+0.622	+0.396	<.001	<.001	3	7
COAD	SLBP →	+0.400	+0.522	.004	.001	3	6
HNSC	PRC1_T481 →	+1.138	+0.651	<.001	<.001	3	6
COAD	RACGAP1 →	+0.622	+0.508	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,459 associations by consensus.

CLN6 vs PRIM2 — GBM

Explore this scatter interactively →