CLN6

Across TCGA patient cohorts, CLN6 protein abundance is significantly associated with the RNA expression of many other genes, with 9,587 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLN6-associated genes across cancer lineages are FANCI, PRC1-AS1, and CKS2. Each is linked with CLN6 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLN6-to-partner and partner-to-CLN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLN6 versus FANCI in LSCC, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLN6→partner) and Y-score (partner→CLN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FANCI →	+1.121	+0.617	<.001	<.001	3	4
UCEC	PRC1-AS1 →	+0.613	+0.762	<.001	<.001	3	4
OV	CKS2 →	+0.753	+0.420	.003	.002	3	3
OV	CCDC59 →	+0.530	+0.397	<.001	.004	3	3
OV	GNG7 →	-0.661	-0.430	.004	.002	3	3
OV	PXMP2 →	+0.465	+0.457	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,587 associations by consensus.

CLN6 vs FANCI — LSCC

Explore this scatter interactively →