CLLU1

Across TCGA pan-cancer cohorts, CLLU1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated CLLU1 data layer compared with 1 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CLLU1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CLLU1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and ESCA show a favorable association.

LUAD, ACC, and KIRC are the cancer types where CLLU1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.894	0.739	<.001	69	view →
ACC	OS	Tertile	All	0.314	0.802	.001	49	view →
KIRC	DFS	Tertile	All	0.524	0.676	.002	41	view →
UVM	OS	Tertile	III,IV	0.120	0.833	<.001	36	view →
THYM	DFS	Tertile	All	0.718	0.977	<.001	36	view →
ESCA	OS	Tertile	III,IV	0.744	0.303	<.001	32	view →
MESO	DFS	Tertile	III,IV	0.264	0.499	.009	27	view →
SKCM	DFS	Tertile	II,III,IV	0.346	0.179	.009	26	view →
CESC	DFS	Tertile	IV	0.199	0.527	.007	24	view →
OV	OS	Median	III,IV	0.367	0.282	.015	22	view →
BLCA	OS	Median	All	0.551	0.221	<.001	21	view →
SCLC	DFS	Tertile	IV	1.000	0.192	.026	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

CLLU1–LUAD (DFS)

Open the LUAD breakdown →