CLLU1

Across TCGA pan-cancer cohorts, CLLU1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of CLLU1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CLLU1 RNA is repressed in tumor relative to normal tissue. In most cancer types CLLU1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and KIRP are the cancer types where CLLU1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLLU1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.060	<.001	9	view →
KIRC	Male	II,III,IV	−0.039	<.001	6	view →
KIRP	Male	All	−0.024	.003	4	view →
LUSC	Male	All	+0.015	.009	3	view →
KICH	All	All	−0.048	.038	2	view →
LUAD	All	All	+0.016	.030	2	view →
COAD	Female	III,IV	+0.016	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

CLLU1–THCA

Open the THCA breakdown →