Across TCGA pan-cancer cohorts, CLK3P2 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of CLK3P2’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CLK3P2 RNA is repressed in tumor relative to normal tissue. In most cancer types CLK3P2 is over-expressed in tumor, although a few such as BRCA and COAD show the opposite, repressed pattern.

BRCA, KIRP, and COAD are the cancer types where CLK3P2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLK3P2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.250	<.001	6	view →
KIRP	Male	All	+0.030	.026	4	view →
COAD	All	II,III,IV	−0.023	.009	4	view →
LUSC	All	All	+0.063	.021	2	view →
HNSC	All	All	+0.119	.027	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: CLK3P2 RNA expression & survival · all CLK3P2 data types