CLK2

Across TCGA patient cohorts, CLK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,310 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLK2-associated proteins across cancer lineages are DHX9, GATAD2B, and TCERG1. Each is linked with CLK2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CLK2-to-partner and partner-to-CLK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLK2 versus DHX9 in LSCC, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLK2→partner) and Y-score (partner→CLK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DHX9 →	+0.305	+0.538	<.001	<.001	3	9
GBM	GATAD2B →	+0.373	+0.431	<.001	<.001	3	9
GBM	TCERG1 →	+0.298	+0.283	<.001	<.001	3	8
HNSC	TRRAP →	+0.321	+0.594	<.001	<.001	3	8
LSCC	POGZ →	+0.330	+0.542	<.001	<.001	3	8
LSCC	WDR5 →	+0.288	+0.494	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,310 associations by consensus.

CLK2 vs DHX9 — LSCC

Explore this scatter interactively →