CLIP1-AS1

Across TCGA pan-cancer cohorts, CLIP1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated CLIP1-AS1 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher CLIP1-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated CLIP1-AS1 expression acts as an unfavorable survival marker, although some lineages such as SKCM and BRCA show a favorable association.

SKCM, UVM, and BRCA are the cancer types where CLIP1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	DFS	Tertile	II,III,IV	0.322	0.157	.001	54	view →
UVM	OS	Median	II,III,IV	0.703	0.913	.004	51	view →
BRCA	OS	Median	All	0.944	0.905	.002	46	view →
LUAD	DFS	Quartile	II,III,IV	0.449	0.679	.016	28	view →
PRAD	DFS	Tertile	All	0.737	0.894	.003	28	view →
KIRC	DFS	Quartile	All	0.535	0.729	.004	27	view →
KIRP	DFS	Tertile	IV	0.485	0.816	.006	26	view →
KICH	DFS	Quartile	II,III,IV	0.188	0.874	.004	25	view →
LGG	OS	Quartile	All	0.357	0.598	<.001	25	view →
ACC	OS	Median	II,III,IV	1.000	0.700	.004	19	view →
ESCA	OS	Quartile	III,IV	0.691	0.280	.013	12	view →
COAD	OS	Tertile	II,III,IV	0.433	0.718	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

CLIP1-AS1–SKCM (DFS)

Open the SKCM breakdown →