CLIP1-AS1

Across TCGA pan-cancer cohorts, CLIP1-AS1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of CLIP1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where CLIP1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CLIP1-AS1 is over-expressed in tumor, although a few such as THCA and BLCA show the opposite, repressed pattern.

THCA, KICH, and BLCA are the cancer types where CLIP1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CLIP1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.287	<.001	10	view →
KICH	All	All	+0.275	<.001	7	view →
BLCA	Female	All	−0.078	.009	3	view →
BRCA	All	III,IV	−0.090	.008	2	view →
HNSC	Male	II,III,IV	+0.079	.004	2	view →
LIHC	Male	All	+0.052	.007	2	view →
KIRC	All	All	+0.035	.019	2	view →
COAD	All	II,III,IV	+0.025	.040	2	view →
STAD	All	IV	+0.123	.033	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

CLIP1-AS1–THCA

Open the THCA breakdown →