CLIC5

Across TCGA patient cohorts, CLIC5 protein abundance is significantly associated with the RNA expression of many other genes, with 16,642 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CLIC5-associated genes across cancer lineages are KIF14, ABCA8, and ENPP4. Each is linked with CLIC5 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLIC5-to-partner and partner-to-CLIC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLIC5 versus KIF14 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLIC5→partner) and Y-score (partner→CLIC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	KIF14 →	-0.922	-0.760	<.001	<.001	3	6
BRCA	ABCA8 →	+1.398	+0.757	<.001	<.001	3	6
BRCA	ENPP4 →	+0.973	+0.601	<.001	.001	3	6
BRCA	INMT →	+1.217	+0.716	<.001	.001	3	6
OV	FOXM1 →	-1.124	-0.769	<.001	.008	3	6
UCEC	POLQ →	-1.095	-0.743	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,642 associations by consensus.

CLIC5 vs KIF14 — UCEC

Explore this scatter interactively →